To characterize the clinical options of human immunodeficiency virus (HIV)-related fever of unknown origin (FUO) in the United States, we carried out a retrospective analysis of cases that fulfilled specific standards (revealed by Durack and Avenue in 1991) at two medical centers within the United States between 1992 and 1997. Seventy cases met standards for HIV-associated FUO; the mean CD4 cell rely was 58/mm3, and the imply duration of fever was forty two days. A trigger of FUO was found in 56 of the 70 cases; 43 were of a single etiology, and in 13 cases a number of conditions have been established. The most common diagnoses had been disseminated Mycobacterium avium infection (DMAC; 31%), Pneumocystis carinii pneumonia (13%), cytomegalovirus infection (11%), disseminated histoplasmosis (7%), and lymphoma (7%). In this United States series, FUO happens most often in the late stage of HIV infection, particular person instances typically have a number of etiologies, and DMAC is the most typical diagnosis.
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